Analysis of driven nanorod transport through a biopolymer matrix

Autor:	Pavel Stepanov, Stephanie Himelfarb, Mario Urdaneta, Irving N. Weinberg, Richard Superfine, Lamar O. Mair, Alek Nacev, Ryan Hilaman
Rok vydání:	2015
Předmět:	Range (particle radiation) Materials science Nanotechnology Matrix (biology) engineering.material Condensed Matter Physics Article Viscoelasticity Electronic Optical and Magnetic Materials Magnetic field engineering Magnetic nanoparticles Particle Nanorod Biopolymer
Zdroj:	Journal of Magnetism and Magnetic Materials. 380:295-298
ISSN:	0304-8853
DOI:	10.1016/j.jmmm.2014.09.059
Popis:	Applying magnetic fields to guide and retain drug-loaded magnetic particles in vivo has been proposed as a way of treating illnesses. Largely, these efforts have been targeted at tumors. One significant barrier to long range transport within tumors is the extracellular matrix (ECM). We perform single particle measurements of 18 nm diameter nanorods undergoing magnetophoresis through ECM, and analyze the motion of these nanorods in two dimensions. We observe intra-particle magnetophoresis in this viscoelastic environment and measure the fraction of time these nanorods spend effectively hindered, versus effectively translating.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dee3cd7dee30e1dcfa698c209b73ed7 https://doi.org/10.1016/j.jmmm.2014.09.059 Zobrazit plný text záznamu Full Text from ScienceDirect