Toxicity, Physical Function and Everyday Activity Reported by Patients with Inoperable Non-Small Cell Lung Cancer in a Randomized Trial (Chemotherapy Versus Radiotherapy)
| Autor: | A Mastekaasa, Stein Kaasa, Erik Thorud |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
medicine.medical_specialty
Lung Neoplasms Nausea medicine.medical_treatment law.invention Radiotherapy High-Energy Random Allocation Randomized controlled trial law Carcinoma Non-Small-Cell Lung Surveys and Questionnaires medicine Humans Radiology Nuclear Medicine and imaging Lung cancer Etoposide Clinical Trials as Topic Chemotherapy business.industry Combination chemotherapy Hematology General Medicine medicine.disease Surgery Radiation therapy Oncology Quality of Life Vomiting Cisplatin medicine.symptom business medicine.drug |
| Zdroj: | Acta Oncologica. 27:343-349 |
| ISSN: | 1651-226X 0284-186X |
| DOI: | 10.3109/02841868809093552 |
| Popis: | In a randomized trial, patients with inoperable non-small cell lung cancer with limited disease were randomly given either radiotherapy (42 Gy) or combination chemotherapy with cisplatin, 70 mg/m2, and etoposide, 100 mg/m2, given every third week with a maximum of 4 cycles. The patients were asked to fill in a questionnaire concerning psychosocial well-being, medical and treatment related symptoms, physical function and everyday activity. Of the chemotherapy patients 61% reported nausea 5 weeks after their last chemotherapy session and 44% had spells of vomiting. Only 14% of the radiotherapy patients had nausea and 5% vomited 14 weeks after start of treatment. Of the radiotherapy patients 64% experienced dysphagia compared to 8% of the chemotherapy patients 6 weeks after the start of treatment. |
| Databáze: | OpenAIRE |
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