Detection and credibility of sentinel node in vulvar cancer: a single institutional study and short review of literature
| Autor: | Maria Sotiropoulou, Dimitrios Haidopoulos, Maria Simou, Nikolaos Akrivos, Alexandros Rodolakis, Aris Antsaklis, George Vlachos, Vasileios Papantoniou, Ioannis Biliatis, Nikolaos Thomakos |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Adult
medicine.medical_specialty medicine.medical_treatment Sentinel lymph node chemistry.chemical_element Technetium chemistry.chemical_compound Predictive Value of Tests medicine Humans Radionuclide Imaging Aged Aged 80 and over Blue dye Vulvar Neoplasms Groin Sentinel Lymph Node Biopsy business.industry Obstetrics and Gynecology General Medicine Middle Aged Vulvar cancer Sentinel node medicine.disease Surgery Methylene Blue medicine.anatomical_structure chemistry Lymphatic Metastasis Technetium Tc 99m Sulfur Colloid Lymph Node Excision Female Lymphadenectomy Lymph Nodes Radiology business Methylene blue |
| Zdroj: | Archives of Gynecology and Obstetrics. 284:1551-1556 |
| ISSN: | 1432-0711 0932-0067 |
| DOI: | 10.1007/s00404-011-1884-z |
| Popis: | To evaluate the detectability and credibility of sentinel lymph node (SLN) in vulvar cancer. With Tc99m-nanocolloid and methylene blue, we identified SLNs in 34 patients. In 27 cases both tracers were used, while in 7 only blue dye was used. Completion lymphadenectomy was performed in all patients. SLNs and non-SLNs were sent separately for pathologic evaluation. At least one SLN was identified in all patients. Detection rate per groin was not significantly higher in the combined versus blue dye only technique (42/50 vs. 10/14, p = 0.43). 99m-Tc was not superior to blue dye in detecting SLN (42/50 vs. 50/64, p = 0.65). Midline location of the tumor did not seem to negatively affect the procedure. Four false negatives were observed in three patients with tumors >4 cm. Negative predictive value of SLN was 100% for grade I tumors ≤4 cm in patients ≤71 years. Tc-99m does not seem to be superior to methylene blue in the detection of SLN in vulvar cancer. Patients of younger age with small, well-differentiated tumors appear to be the most suitable candidates for lymphatic mapping. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink