Detection of Flaviviral-Like DNA Sequences in Aedes aegypti (Diptera: Culicidae) Collected From Argentina
| Autor: | Jorge Adrian Barneche, María Victoria Micieli, Melisa Berenice Bonica, Ailen Chuchuy, Dario Balcazar, Carolina Torres |
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| Rok vydání: | 2021 |
| Předmět: |
viruses
030231 tropical medicine Argentina Aedes aegypti Genome DNA sequencing Dengue fever 03 medical and health sciences 0302 clinical medicine Aedes medicine Encephalitis Viruses Animals 030304 developmental biology 0303 health sciences Genetic diversity General Veterinary biology Flavivirus Yellow fever virus diseases medicine.disease biology.organism_classification Virology Infectious Diseases Insect Science DNA Viral Parasitology |
| Zdroj: | Journal of Medical Entomology. 58:2406-2411 |
| ISSN: | 1938-2928 0022-2585 |
| DOI: | 10.1093/jme/tjab073 |
| Popis: | Diseases caused by flaviviruses are a major public health burden across the world. In the past decades, South America has suffered dengue epidemics, the re-emergence of yellow fever and St. Louis encephalitis viruses, and the introduction of West Nile and Zika viruses. Many insect-specific flaviviruses (ISFs) that cannot replicate in vertebrate cells have recently been described. In this study, we analyzed field-collected mosquito samples from six different ecoregions of Argentina to detect flaviviruses. We did not find any RNA belonging to pathogenic flaviviruses or ISFs in adults or immature stages. However, flaviviral-like DNA similar to flavivirus NS5 region was detected in 83–100% of Aedes aegypti (L.). Despite being previously described as an ancient element in the Ae. aegypti genome, the flaviviral-like DNA sequence was not detected in all Ae. aegypti samples and sequences obtained did not form a monophyletic group, possibly reflecting the genetic diversity of mosquito populations in Argentina. |
| Databáze: | OpenAIRE |
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