Microgrooves and microrugosities in titanium implant surfaces: an in vitro and in vivo evaluation
| Autor: | Jaime Aramburú Júnior, Sergio Alexandre Gehrke, Juan Manuel Aragoneses, Leticia Pérez-Díaz, José Henrique Cavalcanti de Lima, Piedad N. De Aza, Fernando Rodriguez, José Luis Calvo-Guirado, Patricia Mazón |
|---|---|
| Přispěvatelé: | Gehrke S.A., Cavalcanti de Lima J.H., Rodríguez Fernando, Aramburú Júnior J., Pérez-Díaz Leticia, Universidad de la República (Uruguay). Facultad de Ciencias. Instituto de Química Biológica., Mazón P., Aragoneses J.M., De Aza P.N. |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Materials science
Surface treatment 02 engineering and technology Surface finish Bone healing lcsh:Technology Osseointegration Article 03 medical and health sciences 0302 clinical medicine In vivo dental implants Microgrooves General Materials Science Tibia lcsh:Microscopy lcsh:QC120-168.85 lcsh:QH201-278.5 lcsh:T Dental implants osseointegration 030206 dentistry surface treatment 021001 nanoscience & nanotechnology Surface energy In vitro lcsh:TA1-2040 lcsh:Descriptive and experimental mechanics Implant lcsh:Electrical engineering. Electronics. Nuclear engineering bone healing 0210 nano-technology lcsh:Engineering (General). Civil engineering (General) lcsh:TK1-9971 microgrooves Biomedical engineering |
| Zdroj: | COLIBRI Universidad de la República instacron:Universidad de la República Materials, Vol 12, Iss 8, p 1287 (2019) Materials Volume 12 Issue 8 |
| Popis: | The physical characteristics of an implant surface can determine and/or facilitate osseointegration processes. In this sense, a new implant surface with microgrooves associated with plus double acid treatment to generate roughness was evaluated and compared in vitro and in vivo with a non-treated (smooth) and double acid surface treatment. Thirty disks and thirty-six conical implants manufactured from commercially pure titanium (grade IV) were prepared for this study. Three groups were determined, as described below: Group 1 (G1), where the samples were only machined group 2 (G2), where the samples were machined and had their surface treated to generate roughness and test group 3 (G3), where the samples were machined with microgrooves and the surface was treated to generate the roughness. For the in vitro analysis, the samples were submitted to scanning microscopy (SEM), surface profilometry, the atomic force microscope (MFA) and the surface energy test. For the in vivo analyses, thirty-six implants were placed in the tibia of 9 New Zealand rabbits in a randomized manner, after histological and histomorphometric analysis, to determine the level of contact between the bone and implant (BIC%) and the bone area fraction occupancy (BAFO%) inside of the threads. The data collected were statistically analyzed between groups (p < 0.05). The in vitro evaluations showed different roughness patterns between the groups, and the G3 group had the highest values. In vivo evaluations of the BIC% showed 50.45 ± 9.57% for the G1 group, 55.32 ± 10.31% for the G2 group and 68.65 ± 9.98% for the G3 group, with significant statistical difference between the groups (p < 0.0001). In the BAFO% values, the G1 group presented 54.97 ± 9.56%, the G2 group 59.09 ± 10.13% and the G3 group 70.12 ± 11.07%, with statistical difference between the groups (p < 0.001). The results obtained in the evaluations show that the surface with microgrooves stimulates the process of osseointegration, accelerating the healing process, increasing the contact between the bone and the implant and the area of new bone formation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|