Interpregnancy Weight Change and Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis

Autor: Ana Díez-Fernández, Jose Alberto Martínez-Hortelano, Iván Cavero-Redondo, Celia Álvarez-Bueno, Montserrat Hernández-Luengo, Vicente Martínez-Vizcaíno
Rok vydání: 2019
Předmět:
Zdroj: SSRN Electronic Journal.
ISSN: 1556-5068
DOI: 10.2139/ssrn.3506153
Popis: Background: Evidence supports the relationship between pre-pregnancy body mass index (BMI) and gestational diabetes mellitus (GDM). However, the association between interpregnancy weight change (IPWC) and GDM in the subsequent pregnancy has been studied less. The purpose of this study was to conduct a systematic review and meta-analysis to synthesize evidence on the association between IPWC and GDM in the subsequent pregnancy. Methods: MEDLINE, EMBASE, Cochrane Library and Web of Science were searched from inception through 16 September 2019. The most adjusted relative risk (RR) or odds ratios (OR) and their corresponding 95% confidence intervals (CIs) reported by studies included were used. The ‘no weight change’ category defined by each study was used as the reference category. Findings: 13 articles were included in this systematic review and meta-analyses with a total sample of 529.080 women. The analyses showed higher risk of GDM in the subsequent pregnancy among women with interpregnancy weigh gain (OR = 1.56; 95% CI: 1.30-1.83; I2 = 82.30%; p =
Databáze: OpenAIRE