Sensory Perception and Aging in Model Systems: From the Outside In
| Autor: | Tsung Han Kuo, Tammy P. Chan, Scott D. Pletcher, Nancy J. Linford |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Aging
Sensory processing medicine.medical_treatment media_common.quotation_subject Sensation Nutritional Status Sensory system Environment Biology Models Biological Article Life Expectancy Perception medicine Animals Humans Gustatory system Healthy aging Social Behavior media_common Population Density Extramural Reproduction Nutritional status Cell Biology Circadian Rhythm Seasons Cues Neuroscience Signal Transduction Developmental Biology |
| Zdroj: | Annual Review of Cell and Developmental Biology. 27:759-785 |
| ISSN: | 1530-8995 1081-0706 |
| DOI: | 10.1146/annurev-cellbio-092910-154240 |
| Popis: | Sensory systems provide organisms from bacteria to humans with the ability to interact with the world. Numerous senses have evolved that allow animals to detect and decode cues from sources in both their external and internal environments. Recent advances in understanding the central mechanisms by which the brains of simple organisms evaluate different cues and initiate behavioral decisions, coupled with observations that sensory manipulations are capable of altering organismal lifespan, have opened the door for powerful new research into aging. Although direct links between sensory perception and aging have been established only recently, here we discuss these initial discoveries and evaluate the potential for different forms of sensory processing to modulate lifespan across taxa. Harnessing the neurobiology of simple model systems to study the biological impact of sensory experiences will yield insights into the broad influence of sensory perception in mammals and may help uncover new mechanisms of healthy aging. |
| Databáze: | OpenAIRE |
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