The Use of Calcium Channel Blockers in the Treatment of Coronary Spasm and Atrioventricular Block
| Autor: | Mengting Chu, Jin Qian, Xianping Hua, Hesong Zeng, Xingwei He, Zhenjian Zhang, Bo Gao, Chuanbin Cao |
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| Rok vydání: | 2015 |
| Předmět: |
Coronary angiography
Male medicine.medical_specialty Myocardial ischemia Biophysics Coronary Vasospasm Chest pain Coronary Angiography Biochemistry Diltiazem medicine.artery Internal medicine medicine Humans cardiovascular diseases Atrioventricular Block Chest discomfort business.industry Calcium channel Cardiovascular Agents Cell Biology General Medicine Middle Aged medicine.disease Calcium Channel Blockers medicine.anatomical_structure Right coronary artery cardiovascular system Cardiology Female medicine.symptom business Atrioventricular block Artery |
| Zdroj: | Cell biochemistry and biophysics. 72(2) |
| ISSN: | 1559-0283 |
| Popis: | Calcium channel blockers have been used in the treatment of coronary artery spasm for many years. However, there is insufficient knowledge about their application to treat atrioventricular block caused by coronary spasm. Clinical data of five patients who were diagnosed with coronary spasm caused by atrioventricular block and treated with calcium channel blockers were retrospectively assessed. The patients had varying degrees of atrioventricular block (confirmed by Holter ECG) and myocardial ischemia-like ST–T changes. Two patients were II type I AVB, two patients II type II AVB, and the remaining one patient was III AVB. All patients were all diagnosed with right coronary artery spasm by coronary angiography. The patients were treated with calcium channel blockers. No patient reported recurrence of chest pain or chest discomfort. On Holter ECG monitoring, no significant myocardial ischemia or atrioventricular block was seen. In conclusion, calcium channel blockers are effective and safe in the treatment of atrioventricular block caused by coronary spasm. |
| Databáze: | OpenAIRE |
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