Avaliação do complexo médio-intimal nas artérias carótidas, femorais e subclávia direita para investigação precoce de aterosclerose em pacientes infectados pelo HIV

Autor: Emmanuelle Tenório Albuquerque Madruga Godoi, Juannicelle Tenório Albuquerque Madruga Godoi, Carlos Teixeira Brandt, Heloísa Ramos Lacerda de Melo, Jocelene Tenório Albuquerque Madruga Godoi
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Radiologia Brasileira, Vol 46, Iss 6, Pp 333-340 (2013)
Radiologia Brasileira, Volume: 46, Issue: 6, Pages: 333-340, Published: DEC 2013
Radiologia Brasileira v.46 n.6 2013
Radiologia Brasileira
Colégio Brasileiro de Radiologia e Diagnóstico por Imagem (CBR)
instacron:CBR
ISSN: 1678-7099
Popis: Objective To compare automatic and manual measurements of intima-media complex (IMC) in common carotid, common femoral and right subclavian arteries of HIV-infected patients in relation to a control group, taking into consideration the classical risk factors for atherosclerosis. Materials and Methods The study sample comprised 70 HIV-infected patients and 70 non-HIV-infected controls paired according sex and age. Automatic (gold standard) and manual measurements of IMC were performed in the carotid arteries. Manual measurements were also performed in common femoral and right subclavian arteries. Bland-Altman graphs were utilized in the comparison and the adopted level significance was 5%. Results Intima-media complex alterations were not observed in any of the individuals as the mean automatic measurement in the right common carotid (RCC) artery was considered as the gold standard. As the gold standard was compared with the manual measurements (mean, maximum and minimum), no clinically significant alteration was observed. As the gold standard was compared with other sites, the difference was statistically and clinically significant at the origin of right subclavian artery (RCC: 0.51 mm vs. 0.91 mm) (p < 0.001). Conclusion HIV-infected individuals are not at higher risk for atherosclerosis than the control population.
Databáze: OpenAIRE