Relationship between albumin excretion rate and aortic stiffness in untreated essential hypertensive patients

Autor: Rosalia Mongiovì, Giovanni Mezzatesta, Giovanni Cerasola, G. Piazza, Giuseppe Mulè, Vito Volpe, Santina Cottone, Giuseppe Andronico, Anna Vadalà, Emilio Nardi
Přispěvatelé: MULE G, COTTONE S, VADALA A, VOLPE V, MEZZATESTA G, MONGIOVI R, PIAZZA G, NARDI E, ANDRONICO G, CERASOLA G
Jazyk: angličtina
Rok vydání: 2004
Předmět:
Popis: Objectives. To evaluate, in a group of nondiabetic essential hypertensive patients with normal renal function, the relationship between albumin excretion rate (AER) and carotid-femoral pulse wave velocity (PWV), as an index of aortic stiffness. Design. Cross-sectional study. Setting. Outpatient hypertension clinic. Subjects. Seventy patients with mild-to-moderate essential hypertension, aged 42 ± 8 years, never pharmacologically treated. All subjects underwent routine laboratory tests, 24-h ambulatory blood pressure (BP) monitoring, measurement of carotid-femoral PWV, by means of a computerized method, and AER. Results. Microalbuminuric patients (AER ≥ 20 μg min−1; n = 19), when compared with normoalbuminuric subjects, showed more elevated 24-h BP (136/88 ± 10/10 vs. 128/83 ± 7/6 mmHg; P
Databáze: OpenAIRE