Suitability and repeatability of a photostress recovery test device, the macular degeneration detector (MDD-2), for diabetes and diabetic retinopathy assessment
| Autor: | Brittany Foerg, Matthew Ratzlaff, James Loughman, Paul P. Connell |
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| Rok vydání: | 2013 |
| Předmět: |
Male
medicine.medical_specialty macular degeneration Light Visual Acuity Significant learning Diagnostic Techniques Ophthalmological Retina Macular Degeneration Diabetes mellitus Ophthalmology diabetic retinopathy assessment medicine Diabetes Mellitus Humans photostress recovery test device Diabetic Retinopathy diabetes business.industry Diabetic retinopathy screening Repeated measures design Reproducibility of Results General Medicine Repeatability Diabetic retinopathy Recovery of Function Macular degeneration Middle Aged medicine.disease photostress device Exercise Test Female business diabetic retinopaty assessment Photic Stimulation Optometry Retinopathy |
| Zdroj: | Articles |
| ISSN: | 1539-2864 |
| Popis: | Background: Diabetic retinopathy can result in impaired photostress recovery time despite normal visual acuity and fundoscopic appearance. The Macular Degeneration Detector (MDD-2) is a novel flash photostress recovery time device. In this study, we examine the repeatability of the MDD-2 in normal and diabetic subjects. Methods: One hundred and ninety one (90 women, 101 men) subjects were recruited and divided into 1 of the 3 study groups (normal controls, n = 40; diabetes no retinopathy, n = 98; nonproliferative diabetic retinopathy, n = 53). Photostress recovery time was measured three times in the study eye using the MDD-2, each measurement separated by a 5-minute interval. Results: Repeated measures analysis of variance revealed no statistically significant learning or fatigue effects on intrameasurement repeatability for any group. Photostress recovery time measures were broadly similar and typically not statistically significantly different between study groups. The coefficient of repeatability reached clinically acceptable levels once the initial photostress recovery time measure, which demonstrated increased variability and latency compared with all subsequent measures, was excluded. Conclusion: The MDD-2 seems to provide repeatable photostress recovery time measurements among naive diabetic subjects. The device does not, however, seem capable of differentiating normal and nonproliferative diabetic eyes, and would not be suitable for inclusion in diabetic retinopathy screening protocol. |
| Databáze: | OpenAIRE |
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