Choroidal thickness and myopia in relation to physical activity - the CHAMPS Eye Study

Autor: Anders Højslet Vestergaard, Nina Jacobsen, Rasmus Søgaard Hansen, Ulrich Halekoh, Ernst Goldschmidt, Jakob Grauslund, Tunde Peto, Niels Wedderkopp, Kristian Lundberg, Anne Suhr Thykjær
Rok vydání: 2017
Předmět:
Male
Refractive error
Fovea Centralis
visual acuity
genetic structures
Denmark
physical activity
Severity of Illness Index
Tomography
Optical Coherence/methods
0302 clinical medicine
Exercise/physiology
Accelerometry
Myopia
Medicine
refractive error
Prospective Studies
Prospective cohort study
education.field_of_study
exercise
medicine.diagnostic_test
Incidence
Cycloplegia
Fovea Centralis/pathology
General Medicine
Axial Length
Eye
Eye examination
Axial Length
Eye/pathology
Female
medicine.symptom
Tomography
Optical Coherence
medicine.medical_specialty
Biometry
Adolescent
Choroid/diagnostic imaging
Population
axial length
03 medical and health sciences
children
Optical coherence tomography
Ophthalmology
Linear regression
Humans
myopia
education
Exercise
business.industry
Choroid
030229 sport sciences
medicine.disease
Denmark/epidemiology
eye diseases
Intensity (physics)
Myopia/diagnosis
030221 ophthalmology & optometry
sense organs
business
Follow-Up Studies
Zdroj: Lundberg, K, Vestergaard, A H, Jacobsen, N, Suhr Thykjaer, A, Søgaard Hansen, R, Goldschmidt, E, Peto, T, Halekoh, U, Wedderkopp, N & Grauslund, J 2018, ' Choroidal thickness and myopia in relation to physical activity-the CHAMPS Eye Study ', Acta Ophthalmologica, vol. 96, no. 4, pp. 371-378 . https://doi.org/10.1111/aos.13640
ISSN: 1755-3768
DOI: 10.1111/aos.13640
Popis: PURPOSE: To describe the relationship between choroidal thickness (CT) and myopia in relation to physical activity (PA) in a population-based child cohort.METHODS: In a prospective study of 307 children from the CHAMPS Study Denmark, we used objective data from GT3X accelerometer worn at four periods between 2009 and 2015 to determine the amount and intensity of PA. Intensity was estimated as counts/minutes, and cut-off points were defined at four intensity levels. Eye examinations were performed in 2015 and included autorefraction in cycloplegia, axial length (AL) by biometric and fovea-centred enhanced depth imaging optical coherence tomography. By a semi-automated method, we measured the CT at 17 targets per eye representing anatomically different locations (subfoveal, 1 and 3 millimetre in each direction of fovea).RESULTS: Mean age at the eye examination was 15.4 ± 0.7 years. The mean AL was 23.5 ± 0.9 mm, and the mean subfoveal CT was 369 ± 87 μm. Choroidal thickness (CT) was 331 ± 68 μm for the overall macula, 355 ± 78 μm for the 1-mm zone and 304 ± 60 μm for the 3-mm zone. All CT measurements were thinner in myopic eyes (p < 0.0001) and in boys (p < 0.05). We found no association between total PA and the CT by either mixed model analysis (p = 0.074) or linear regression by any intensity levels (p = 0.22, p = 0.15 and p = 0.43).CONCLUSION: Among adolescents aged 14-17 years, there was no association between objective PA exposures and the CT, AL or refractive error.
Databáze: OpenAIRE
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