Portal venous flow during CO(2) pneumoperitoneum in the rat
| Autor: | C. N. Gutt, Th. Schmandra |
|---|---|
| Rok vydání: | 1999 |
| Předmět: |
Insufflation
Male business.industry Portal Vein Portal venous pressure Blood flow Carbon Dioxide medicine.disease Venous flow Rats Abdominal wall Rats Sprague-Dawley medicine.anatomical_structure Pneumoperitoneum Co2 pneumoperitoneum Anesthesia Abdomen medicine Pressure Animals Surgery business Pneumoperitoneum Artificial Blood Flow Velocity Abdominal surgery |
| Zdroj: | Surgical endoscopy. 13(9) |
| ISSN: | 0930-2794 |
| Popis: | CO(2) gas insufflation is routinely used to extend the abdominal wall. The resulting pneumoperitoneum has a number of local and systemic effects on the organism. Portal blood flow, which plays an important role in hepatic function and cell-conveyed immune response, is one of the affected parameters.An established animal model (rat) of laparoscopic surgery was modified by implanting a perivascular flow probe. Hemodynamics in the portal vein were then measured during increasing intraabdominal pressure generated by carbon dioxide insufflation.Using this technique, an adequate flowmetry of the portal vein was achieved in all animals. The creation of a CO(2) pneumoperitoneum with increasing intraabdominal pressure led to a linear decrease in portal venous flow.Elevated intraabdominal pressure caused by carbon dioxide insufflation may compromise hepatic function and cell-conveyed immune response during laparoscopic surgery. |
| Databáze: | OpenAIRE |
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