Conformational Changes in 16 S Ribosomal RNA Induced by 30 S Ribosomal Subunit Proteins from Escherichia coli

Autor:	Alexei A. Bogdanov, Robert A. Zimmermann, Norman C. Ford, Chun-Chen Wang
Rok vydání:	1978
Předmět:	Ribosomal Proteins Riboswitch Multidisciplinary RNA Biology Ribosome Molecular biology Diffusion RNA Bacterial 5S ribosomal RNA Bacterial Proteins Ribonucleoproteins RNA Ribosomal Transfer RNA Escherichia coli Biophysics Nucleic Acid Conformation 30S Degradosome Ribosomes Protein Binding 50S
Zdroj:	Science. 202:999-1001
ISSN:	1095-9203 0036-8075
DOI:	10.1126/science.362531
Popis:	Laser light scattering has been used to evaluate conformational differences between free 16S RNA and several specific protein-16S RNA complexes. Proteins that interact strongly with the 16S RNA early in subunit assembly stabilize the RNA chain against unfolding in 1 mM Mg2+ and actually promote the formation of a more compact teriary structure in 20 mM Mg2+. A vital function of these proteins may therfore consist in altering the configuration of the RNA so that further assembly reactions can take place.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d97d3db3e90f70b68f887c2077bec4e https://doi.org/10.1126/science.362531 Zobrazit plný text záznamu