Intraparenchymal metastases as a cause for local recurrence of pancreatic cancer

Autor:	Ashley L Kiemen, YoungGeun Choi, Alicia M Braxton, Cristina Almagro Pérez, Sarah Graham, Mia P Grahn, Neha Nanda, Nicholas Roberts, Laura Wood, PeiHsun Wu, Ralph H Hruban, Denis Wirtz
Rok vydání:	2022
Předmět:	Histology General Medicine Article Pathology and Forensic Medicine
Zdroj:	Histopathology
ISSN:	1365-2559 0309-0167
DOI:	10.1111/his.14839
Popis:	Using CODA, a technique for three-dimensional reconstruction of large tissues, Kiemen et al. report observation of a microscopic focus of pancreatic cancer found in the vasculature of grossly normal human pancreas tissue resected adjacent to a large tumour. They use TP53 and SMAD4 staining to relate the small focus to the primary tumour. This report describes a represents a probable case of intraparenchymal metastasis of pancreatic cancer, revealing a probable cause of local recurrence.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d973b7b1730e6bb405c70cea467fea3 https://doi.org/10.1111/his.14839 Zobrazit plný text záznamu Plný text