Iridium-catalyzed stereoselective [3+2] annulation of α-oxocarboxylic acids with 1,3-dienes
| Autor: | Takahiro Nishimura, Yusuke Ebe, Ryota Yabe |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Annulation
Diene Chemistry Ligand Metals and Alloys Cationic polymerization chemistry.chemical_element General Chemistry Medicinal chemistry Catalysis Surfaces Coatings and Films Electronic Optical and Magnetic Materials chemistry.chemical_compound Materials Chemistry Ceramics and Composites Stereoselectivity Iridium |
| Zdroj: | Chemical communications (Cambridge, England). 57(48) |
| ISSN: | 1364-548X |
| Popis: | The stereoselective annulation of α-oxocarboxylic acids with 1,3-dienes proceeded in the presence of a hydroxoiridium catalyst to give α-hydroxy-γ-lactones in good yields with high 3,5-trans relative stereochemistry. The use of a chiral diene ligand for a cationic iridium complex enabled asymmetric annulation with high enantioselectivity. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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