STIMULATION BY STEROIDS AND AGE-DEPENDENT CHANGES OF L-CYSTINE ARYLAMIDASE ACTIVITY IN THE HYPOTHALAMUS OF THE RAT
| Autor: | Christian Rosniatowski, Martin Bickel, Hans-Dieter Taubert, Herbert Kuhl |
|---|---|
| Rok vydání: | 1974 |
| Předmět: |
Male
medicine.medical_specialty Endocrinology Diabetes and Metabolism Population Hypothalamus Stimulation Ethinyl Estradiol Aminopeptidases Sex Factors Endocrinology Internal medicine Ethinylestradiol medicine Animals Sexual maturity Testosterone education education.field_of_study Aniline Compounds biology business.industry Age Factors General Medicine Hydrogen-Ion Concentration Stimulation Chemical Enzyme assay Rats biology.protein Cystine Female business Hormone medicine.drug |
| Zdroj: | Acta Endocrinologica. 76:15-23 |
| ISSN: | 1479-683X 0804-4643 |
| Popis: | L-cystine arylamidase activity was found to be high in hypothalamic homogenates from 10 day old rats, and then to decrease significantly until sexual maturity was reached (P < 0.01). This enzyme activity could be stimulated by treating 10 to 35 day old male rats with 100 μg of testosterone. Contrary to this, L-cystine arylamidase activity could not be stimulated in female animals by the injection of 7 μg of ethinyl-oestradiol before Day 45 of life. These data are interpreted as meaning that the L-cystine arylamidase activity plays a rôle in the processes regulating sexual maturation. |
| Databáze: | OpenAIRE |
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