Serum lipid and glucose profiles in HIV-positive Nigerian children
| Autor: | Christopher S Yilgwan, Augustine O. Ebonyi, Esther S. Yiltok, Stephen Oguche, Fidelia Bode-Thomas, Idris Abiodun Adedeji, Ruth O. Adah, Olukemi O Ige |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
dyslipidaemia Epidemiology Immunology Human immunodeficiency virus (HIV) Nigeria medicine.disease_cause Logistic regression Microbiology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine 030225 pediatrics Virology Internal medicine Paediatric infectious disease clinic medicine 030212 general & internal medicine Original Research Triglyceride business.industry HIV-positive children Public Health Environmental and Occupational Health Lopinavir Confidence interval QR1-502 cardiovascular disease risk Infectious Diseases chemistry Ritonavir University teaching Public aspects of medicine RA1-1270 business hyperglycaemia medicine.drug |
| Zdroj: | Journal of Virus Eradication Web of Science Journal of Virus Eradication, Vol 3, Iss 3, Pp 157-162 (2017) |
| ISSN: | 2055-6659 2055-6640 |
| Popis: | Objectives To describe the fasting serum lipid and glucose profiles of HIV-positive Nigerian children and determine the prevalence and risk factors for dyslipidaemia and hyperglycaemia, which are risk factors for cardiovascular diseases. Methods This was a comparative cross-sectional study carried out at the Paediatric Infectious Disease Clinic (PIDC) of the Jos University Teaching Hospital (JUTH) for HIV-positive children and at two primary schools in Jos for HIV-negative children as controls. One hundred and forty-two HIV-positive children aged 6–18 years and an equal number of controls were studied by determining their fasting serum lipid and glucose levels. The prevalence of dyslipidaemia and hyperglycaemia was determined and their risk factors obtained using multivariate logistic regression. P values of less than 0.05 were considered statistically significant. Results Mean triglyceride levels were significantly higher in HIV-positive children compared with controls at 87.2 mg/dL (95% confidence interval [CI] 79.4–95.0) and 68.1 mg/dL (95% CI 62.5–72.7), respectively (P |
| Databáze: | OpenAIRE |
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