Spike Avalanches Exhibit Universal Dynamics across the Sleep-Wake Cycle

Autor: Mauro Copelli, Miguel A. L. Nicolelis, Fabio Viegas Caixeta, Tiago L. Ribeiro, Dante R. Chialvo, Sidarta Ribeiro, Hindiael Belchior
Rok vydání: 2011
Předmět:
Male
Action Potentials
Hippocampus
lcsh:Medicine
Synaptic Transmission
01 natural sciences
Power law
0302 clinical medicine
Anesthesiology and Pain Management/Anesthetic Mechanisms
Anesthesia
lcsh:Science
Cerebral Cortex
Neurons
Physics
Neuroscience/Behavioral Neuroscience
Multidisciplinary
Brain
Physiology/Neural Homeostasis
medicine.anatomical_structure
Cerebral cortex
Log-normal distribution
Spike (software development)
Wakefulness
Neurons and Cognition (q-bio.NC)
Research Article
Models
Neurological
Computational Biology/Computational Neuroscience
FOS: Physical sciences
Sensory system
Physics/Interdisciplinary Physics
03 medical and health sciences
0103 physical sciences
medicine
Animals
Rats
Long-Evans
Neuroscience/Theoretical Neuroscience
010306 general physics
Quantitative Biology::Neurons and Cognition
Neuroscience/Sensory Systems
lcsh:R
Rats
Quantitative Biology - Neurons and Cognition
Physics - Data Analysis
Statistics and Probability
FOS: Biological sciences
Detrended fluctuation analysis
lcsh:Q
Sleep
Neuroscience
030217 neurology & neurosurgery
Data Analysis
Statistics and Probability (physics.data-an)
Zdroj: PLoS ONE, Vol 5, Iss 11, p e14129 (2010)
PLoS ONE
DOI: 10.48550/arxiv.1101.2434
Popis: Scale-invariant neuronal avalanches have been observed in cell cultures and slices as well as anesthetized and awake brains, suggesting that the brain operates near criticality, i.e. within a narrow margin between avalanche propagation and extinction. In theory, criticality provides many desirable features for the behaving brain, optimizing computational capabilities, information transmission, sensitivity to sensory stimuli and size of memory repertoires. However, a thorough characterization of neuronal avalanches in freely-behaving (FB) animals is still missing, thus raising doubts about their relevance for brain function. To address this issue, we employed chronically implanted multielectrode arrays (MEA) to record avalanches of spikes from the cerebral cortex (V1 and S1) and hippocampus (HP) of 14 rats, as they spontaneously traversed the wake-sleep cycle, explored novel objects or were subjected to anesthesia (AN). We then modeled spike avalanches to evaluate the impact of sparse MEA sampling on their statistics. We found that the size distribution of spike avalanches are well fit by lognormal distributions in FB animals, and by truncated power laws in the AN group. The FB data are also characterized by multiple key features compatible with criticality in the temporal domain, such as 1/f spectra and long-term correlations as measured by detrended fluctuation analysis. These signatures are very stable across waking, slow-wave sleep and rapid-eye-movement sleep, but collapse during anesthesia. Likewise, waiting time distributions obey a single scaling function during all natural behavioral states, but not during anesthesia. Results are equivalent for neuronal ensembles recorded from V1, S1 and HP. Altogether, the data provide a comprehensive link between behavior and brain criticality, revealing a unique scale-invariant regime of spike avalanches across all major behaviors.
Comment: 14 pages, 9 figures, supporting material included (published in Plos One)
Databáze: OpenAIRE
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