Cortisol In Vivo Increases FSHβ mRNA Selectively in Pituitaries of Male Rats
| Autor: | Joanne M. McAndrews, Sonia J. Ringstrom, Jason O. Rahal, Neena B. Schwartz |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Male
endocrine system Pituitary gland medicine.medical_specialty Hydrocortisone Alpha (ethology) Biology Endocrinology In vivo Internal medicine medicine Animals RNA Messenger Orchiectomy Beta (finance) Sex Characteristics Rats Inbred Strains Luteinizing Hormone Rats medicine.anatomical_structure Pituitary Gland Follicle Stimulating Hormone hormones hormone substitutes and hormone antagonists Glucocorticoid medicine.drug Endocrine gland |
| Zdroj: | Endocrinology. 129:2793-2795 |
| ISSN: | 1945-7170 0013-7227 |
| DOI: | 10.1210/endo-129-5-2793 |
| Popis: | Cortisol treatment for 6 or 12 days had no effect on serum FSH in intact males and animals castrated for 1 or 7 days, but pituitary FSH was increased by the steroid in both intact and castrate groups. In contrast, cortisol inhibited serum LH in both intact and castrated animals while only increasing pituitary levels of LH in 7 day castrates. Cortisol also increased the mRNA for FSH beta without affecting alpha or LH beta mRNAs. These data suggest that the selective increase in pituitary content of FSH may be due to a selective increase in FSH beta mRNA following exposure to cortisol. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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