Left ventricular remodelling and prognosis after discharge in new‐onset acute heart failure with reduced ejection fraction
Autor: | Alina A. Constantinescu, Jan C. van den Berge, Jasper J. Brugts, Maxime M. Vroegindewey, Olivier C. Manintveld, Jaap W. Deckers, Kadir Caliskan, Jesse F. Veenis, Eric Boersma, K. Martijn Akkerhuis |
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Přispěvatelé: | Cardiology |
Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: |
Inotrope
medicine.medical_specialty medicine.medical_treatment 030204 cardiovascular system & hematology Ventricular Function Left Cohort Studies 03 medical and health sciences 0302 clinical medicine Interquartile range Original Research Articles Internal medicine medicine Humans Diseases of the circulatory (Cardiovascular) system LV remodelling Original Research Article 030212 general & internal medicine Heart Failure Heart transplantation Ejection fraction Ventricular Remodeling business.industry Optimal medical treatment Hazard ratio Stroke Volume HFrEF medicine.disease Prognosis Heart failure RC666-701 Circulatory system Cardiology Cardiology and Cardiovascular Medicine Mitral valve regurgitation business |
Zdroj: | ESC Heart Failure, Vol 8, Iss 4, Pp 2679-2689 (2021) ESC heart failure, 8(4), 2679-2689. The Heart Failure Association of the European Society of Cardiology ESC Heart Failure |
ISSN: | 2055-5822 |
Popis: | Aims: This study aimed to investigate the left ventricular (LV) remodelling and long-term prognosis of patients with new-onset acute heart failure (HF) with reduced ejection fraction who were pharmacologically managed and survived until hospital discharge. We compared patients with ischaemic and non-ischaemic aetiology. Methods and results: This cohort study consisted of 111 patients admitted with new-onset acute HF in the period 2008–2016 [62% non-ischaemic aetiology, 48% supported by inotropes, vasopressors, or short-term mechanical circulatory devices, and left ventricular ejection fraction (LVEF) at discharge 28% (interquartile range 22–34)]. LV dimensions, LVEF, and mitral valve regurgitation were used as markers for LV remodelling during up to 3 years of follow-up. Both patients with non-ischaemic and ischaemic HF had significant improvement in LVEF (P |
Databáze: | OpenAIRE |
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