Echocardiographic predictors of acute kidney injury in neonates with a patent ductus arteriosus

Autor: Zachary J Coffman, Jason R. Buckley, Katherine Twombley, Shahryar M. Chowdhury, David Steflik
Rok vydání: 2019
Předmět:
Male
Pediatrics
medicine.medical_specialty
congenital
hereditary
and neonatal diseases and abnormalities
Neonatal intensive care unit
education
Hemodynamics
Gestational Age
Logistic regression
urologic and male genital diseases
Article
03 medical and health sciences
0302 clinical medicine
Predictive Value of Tests
Risk Factors
030225 pediatrics
Ductus arteriosus
Medicine
Birth Weight
Humans
030212 general & internal medicine
Ductus Arteriosus
Patent
Retrospective Studies
business.industry
urogenital system
Incidence (epidemiology)
Acute kidney injury
Infant
Newborn
Obstetrics and Gynecology
Retrospective cohort study
Heart
Acute Kidney Injury
Length of Stay
medicine.disease
female genital diseases and pregnancy complications
medicine.anatomical_structure
Logistic Models
Echocardiography
Pediatrics
Perinatology and Child Health
Gestation
Female
business
Zdroj: J Perinatol
ISSN: 1476-5543
Popis: OBJECTIVE: To investigate acute kidney injury (AKI) in neonates with a patent ductus arteriosus (PDA) including incidence, risk factors, and possible correlations between PDA-related echocardiographic measurements and AKI incidence. STUDY DESIGN: We conducted a single-center retrospective cohort study of infants admitted to the neonatal intensive care unit with a diagnosis of a PDA between July 2015 and July 2017. Infants were evaluated for development of AKI based on the KDIGO criteria and a multivariable logistic regression analysis was performed. RESULTS: A total of 142 neonates with moderate or large PDAs were included, 43 (30%) developed AKI. Patients who developed AKI had longer length of stay, lower birth weights, lengths, and gestational ages. No echocardiographic measurements were predictive of an increased risk for developing AKI. CONCLUSION: There are no significant differences in commonly measured echocardiographic markers of PDA hemodynamic significance in neonates who develop AKI.
Databáze: OpenAIRE
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