Management of Takotsubo Syndrome: A Comprehensive Review
Autor: | Michael Connerney, Kelvin Shenq Woei Siew, M. Chadi Alraies, Waqas Ullah, Yasar Sattar |
---|---|
Rok vydání: | 2020 |
Předmět: |
Inotrope
Acute coronary syndrome medicine.medical_specialty Population Cardiomyopathy Cardiology Ventricular outflow tract obstruction 030204 cardiovascular system & hematology acute coronary syndrome 03 medical and health sciences 0302 clinical medicine Internal medicine left ventricular outflow tract obstruction medicine Internal Medicine takotsubo syndrome education education.field_of_study business.industry Cardiogenic shock General Engineering Warfarin takotsubo cardiomyopathy medicine.disease Cardiac/Thoracic/Vascular Surgery medicine.symptom business cardiomyopathy 030217 neurology & neurosurgery Rare disease medicine.drug |
Zdroj: | Cureus |
ISSN: | 2168-8184 |
Popis: | Takotsubo syndrome (TTS), also known as Takotsubo cardiomyopathy, is a transient left ventricular wall dysfunction that is often triggered by physical or emotional stressors. Although TTS is a rare disease with a prevalence of only 0.5% to 0.9% in the general population, it is often misdiagnosed as acute coronary syndrome. A diagnosis of TTS can be made using Mayo diagnostic criteria. The initial management of TTS includes dual antiplatelet therapy, anticoagulants, beta-blockers, angiotensin-converting enzyme inhibitors or aldosterone receptor blockers, and statins. Treatment is usually provided for up to three months and has a good safety profile. For TTS with complications such as cardiogenic shock, management depends on left ventricular outflow tract obstruction (LVOTO). In patients without LVOTO, inotropic agents can be used to maintain pressure, while inotropic agents are contraindicated in patients with LVOTO. In TTS with thromboembolism, heparin should be started, and patients should be bridged to warfarin for up to three months to prevent systemic emboli. Our comprehensive review discussed the management in detail, derived from the most recent literature from observational studies, systematic review, and meta-analyses. |
Databáze: | OpenAIRE |
Externí odkaz: |