Human chorionic gonadotropin follow-up in patients with molar pregnancy: a time for reevaluation
| Autor: | József Bátorfi, Ross S. Berkowitz, Donald P. Goldstein, Vilmos Fulop, József Doszpod, Colleen M. Feltmate |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Adult
Molar endocrine system medicine.medical_specialty Adolescent medicine.drug_class Chorionic Gonadotropin Medical Records Human chorionic gonadotropin Treatment Refusal Molar pregnancy New England Pregnancy Placenta Outcome Assessment Health Care medicine Humans Registries reproductive and urinary physiology Retrospective Studies Gynecology Diagnostic Tests Routine urogenital system business.industry Obstetrics Medical record Obstetrics and Gynecology Retrospective cohort study Hydatidiform Mole Middle Aged medicine.disease medicine.anatomical_structure Uterine Neoplasms Female Neoplasm Recurrence Local Gonadotropin business hormones hormone substitutes and hormone antagonists |
| Zdroj: | Obstetrics & Gynecology. 101:732-736 |
| ISSN: | 0029-7844 |
| Popis: | Objective To determine how often patients with molar pregnancy do not complete recommended follow-up and to identify factors that may predict failure to complete human chorionic gonadotropin (hCG) monitoring. This study also sought to determine how often patients with molar pregnancy who do not complete follow-up relapse after attaining at least one undetectable hCG value. Methods Four hundred randomly selected patients with molar pregnancy were analyzed regarding the serum hCG levels after molar evacuation. Demographic factors were determined for each patient: age, marital status, gravidity, parity, health insurance type, and distance from patient residence to trophoblastic center. Results Recommended hCG follow-up was completed in 63% of the uncomplicated 333 cases ( n = 211). Three hundred twenty patients achieved at least one undetectable serum hCG level. Among the 320 patients, 33% achieved undetectable hCG values but did not complete recommended follow-up. However, none had any evidence of relapse. A distance of greater than 20 miles from the patient’s residence to our center was associated with failure to complete hCG follow-up ( P = .001). Conclusion Because none of the 320 patients who achieved at least one undetectable hCG level has been diagnosed with gestational trophoblastic tumor relapse, it may be appropriate to reassess the duration of hCG monitoring for patients with molar pregnancy. |
| Databáze: | OpenAIRE |
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