Sentinel nodes identified by computed tomography-lymphography accurately stage the axilla in patients with breast cancer

Autor: Atsushi Noguchi, Katsuyuki Nakanishi, Hiroshi Sumino, Takashi Horinouchi, Kazuyoshi Motomura
Jazyk: angličtina
Předmět:
Zdroj: BMC Medical Imaging
ISSN: 1471-2342
DOI: 10.1186/1471-2342-13-42
Popis: Background Sentinel node biopsy often results in the identification and removal of multiple nodes as sentinel nodes, although most of these nodes could be non-sentinel nodes. This study investigated whether computed tomography-lymphography (CT-LG) can distinguish sentinel nodes from non-sentinel nodes and whether sentinel nodes identified by CT-LG can accurately stage the axilla in patients with breast cancer. Methods This study included 184 patients with breast cancer and clinically negative nodes. Contrast agent was injected interstitially. The location of sentinel nodes was marked on the skin surface using a CT laser light navigator system. Lymph nodes located just under the marks were first removed as sentinel nodes. Then, all dyed nodes or all hot nodes were removed. Results The mean number of sentinel nodes identified by CT-LG was significantly lower than that of dyed and/or hot nodes removed (1.1 vs 1.8, p
Databáze: OpenAIRE