Sentinel nodes identified by computed tomography-lymphography accurately stage the axilla in patients with breast cancer
Autor: | Atsushi Noguchi, Katsuyuki Nakanishi, Hiroshi Sumino, Takashi Horinouchi, Kazuyoshi Motomura |
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Jazyk: | angličtina |
Předmět: |
Adult
medicine.medical_specialty Staging Breast Neoplasms Sensitivity and Specificity Metastasis Breast cancer Japan Risk Factors Node (computer science) Biopsy Prevalence medicine Humans Mammography Radiology Nuclear Medicine and imaging Stage (cooking) Computed tomography Aged Neoplasm Staging medicine.diagnostic_test Sentinel Lymph Node Biopsy business.industry Lymphography Reproducibility of Results Middle Aged Sentinel node medicine.disease Axilla medicine.anatomical_structure Radiology Nuclear Medicine and imaging Lymphatic Metastasis Female Radiology Tomography X-Ray Computed business Research Article |
Zdroj: | BMC Medical Imaging |
ISSN: | 1471-2342 |
DOI: | 10.1186/1471-2342-13-42 |
Popis: | Background Sentinel node biopsy often results in the identification and removal of multiple nodes as sentinel nodes, although most of these nodes could be non-sentinel nodes. This study investigated whether computed tomography-lymphography (CT-LG) can distinguish sentinel nodes from non-sentinel nodes and whether sentinel nodes identified by CT-LG can accurately stage the axilla in patients with breast cancer. Methods This study included 184 patients with breast cancer and clinically negative nodes. Contrast agent was injected interstitially. The location of sentinel nodes was marked on the skin surface using a CT laser light navigator system. Lymph nodes located just under the marks were first removed as sentinel nodes. Then, all dyed nodes or all hot nodes were removed. Results The mean number of sentinel nodes identified by CT-LG was significantly lower than that of dyed and/or hot nodes removed (1.1 vs 1.8, p |
Databáze: | OpenAIRE |
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