Dorsolateral prefrontal cortex-based control with an implanted brain–computer interface
| Autor: | Zac V. Freudenburg, Martine J. E. van Zandvoort, Erik J. Aarnoutse, Elmar Pels, Mariana P. Branco, N.F. Ramsey, Mariska J. Vansteensel, Sacha Leinders, Benny van der Vijgh |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Neuroprosthetics Eye Movements lcsh:Medicine Prefrontal Cortex Electroencephalography Audiology Neuropsychological Tests Article 03 medical and health sciences User-Computer Interface 0302 clinical medicine Cognition Medicine Humans lcsh:Science Brain–computer interface Multidisciplinary medicine.diagnostic_test business.industry lcsh:R Signal source Magnetic resonance imaging Motor impairment Middle Aged Translational research Magnetic Resonance Imaging Dorsolateral prefrontal cortex 030104 developmental biology medicine.anatomical_structure Neurology Brain-Computer Interfaces lcsh:Q Female Locked-In Syndrome business 030217 neurology & neurosurgery Psychomotor Performance |
| Zdroj: | Scientific Reports Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020) |
| ISSN: | 2045-2322 |
| Popis: | The objective of this study was to test the feasibility of using the dorsolateral prefrontal cortex as a signal source for brain–computer interface control in people with severe motor impairment. We implanted two individuals with locked-in syndrome with a chronic brain–computer interface designed to restore independent communication. The implanted system (Utrecht NeuroProsthesis) included electrode strips placed subdurally over the dorsolateral prefrontal cortex. In both participants, counting backwards activated the dorsolateral prefrontal cortex consistently over the course of 47 and 22 months, respectively. Moreover, both participants were able to use this signal to control a cursor in one dimension, with average accuracy scores of 78 ± 9% (standard deviation) and 71 ± 11% (chance level: 50%), respectively. Brain–computer interface control based on dorsolateral prefrontal cortex activity is feasible in people with locked-in syndrome and may become of relevance for those unable to use sensorimotor signals for control. |
| Databáze: | OpenAIRE |
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