Guillain Barré syndrome precipitated by the use of antilymphocyte globulin in the treatment of severe aplastic anaemia
| Autor: | C E Davies, Heather Oakervee, J Gawler, N C Silver, Jamie Cavenagh, B. Kaya |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Globulin
T cell Case Reports Guillain-Barre Syndrome Pathology and Forensic Medicine Autoimmune Diseases hemic and lymphatic diseases medicine Humans Aplastic anemia Depression (differential diagnoses) Antilymphocyte Serum Autoimmune disease biology Guillain-Barre syndrome business.industry Bone marrow failure Anemia Aplastic General Medicine Middle Aged medicine.disease medicine.anatomical_structure Immunology biology.protein Etiology Female business Immunosuppressive Agents |
| Zdroj: | Journal of clinical pathology. 58(9) |
| ISSN: | 0021-9746 |
| Popis: | This report describes the case of a 54 year old woman with very severe aplastic anaemia who was treated with antilymphocyte globulin (ALG) and developed Guillain Barre syndrome (GBS). No antecedent infective aetiology was identified. Although there are numerous reports of autoimmune disease after treatment with ALG in aplastic anaemia, and GBS after immunosuppressive treatment, there are none reporting GBS after the use of ALG for severe aplastic anaemia. The occurrence of autoimmune disease after immunosuppressive treatment, in particular ALG, is discussed, together with the possible mechanisms that result from T cell depression. |
| Databáze: | OpenAIRE |
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