In vivo anticancer activity of lysates from trypanosoma cruzi of different genetic groups
| Autor: | E. G. Kravtsov, Pakhorukova Lv, L. P. Karpenko, M. V. Dalin, V. D. Kallinikova, Zetsegsaikhan Batmonkh |
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| Rok vydání: | 2007 |
| Předmět: |
Antitumor activity
Cell Extracts Lysis biology Trypanosoma cruzi Clone (cell biology) Antineoplastic Agents General Medicine Adenocarcinoma biology.organism_classification medicine.disease Molecular biology General Biochemistry Genetics and Molecular Biology Mice In vivo parasitic diseases Trypanosoma medicine Animals Carcinoma Ehrlich Tumor |
| Zdroj: | Bulletin of experimental biology and medicine. 142(4) |
| ISSN: | 0007-4888 |
| Popis: | Lyzed epimastigotes of Trypanosoma cruzi clones P209-1, Gamba1, Sp104-1, MASu, Y7/1, MN12, Cl-Brener, 86/2036, Y7/2-1 inhibit the growth of Ehrlich adenocarcinoma in mice. the tumor decreased 1.5-3 times after 12 daily injections of lysates from 15 million epimastigotes. The protective effect progressed after the injections were discontinued and depended on the dose and lysate producer clone. Trypanosoma lysates in the studied doses were nontoxic. |
| Databáze: | OpenAIRE |
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