Audiological disturbances in patients with primary antiphospholipid syndrome

Autor:	Zamir Dovrish, Avraham Meyer, Eran Abarbuch, Amed Natour, Aiman Natour, Yair Levy, Daniel Erez
Rok vydání:	2020
Předmět:	Adult Male Pediatrics medicine.medical_specialty Hearing loss Hearing Loss Sensorineural 03 medical and health sciences 0302 clinical medicine Rheumatology Antiphospholipid syndrome Surveys and Questionnaires Hypercoagulability State otorhinolaryngologic diseases medicine Humans In patient Prospective Studies Israel 030223 otorhinolaryngology Aged Aged 80 and over 030203 arthritis & rheumatology Autoimmune disease biology business.industry Middle Aged Antiphospholipid Syndrome medicine.disease Primary antiphospholipid syndrome Case-Control Studies biology.protein Female medicine.symptom Antibody business
Zdroj:	Lupus. 29:533-538
ISSN:	1477-0962 0961-2033
Popis:	Background Antiphospholipid syndrome (APS) is an autoimmune disease of hypercoagulability state in the presence of antibodies against phospholipids. Many neurological deficits related to APS have been described. Sensory neural hearing loss has been described only anecdotally, mostly in case reports. This study investigated a possible association between hearing disorders and APS. Methods Seventeen patients (aged 20–80 years) diagnosed with primary APS were evaluated for evidence of hearing disorders. All had otoscopy, full audiometry test, brainstem evoked response audiometry and otoacoustic emissions testing, and completed a questionnaire. Hearing levels were compared to the standard hearing levels of the general population by age group. Results Of the 17 APS patients, 10 (age groups 20–29 and 50–59) had significantly reduced hearing levels in all or part of the tested frequencies compared to standard levels. Three patients (age group 60–69) had better hearing levels at low frequencies compared to standard hearing levels. Conclusion These findings support the existence of hearing disorders in primary APS.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d55b9140b84fededfea06209a7f0262 https://doi.org/10.1177/0961203320904780 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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