Spine bone mineral density increases after 6 months of exclusive lactation, even in women who keep breastfeeding
| Autor: | Gerald Mugford, Beth J. Kirby, Sandra Cooke-Hubley, James Valcour, Jonathan D. Adachi, Christopher S. Kovacs |
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| Rok vydání: | 2017 |
| Předmět: |
musculoskeletal diseases
0301 basic medicine Adult medicine.medical_specialty Osteoporosis Breastfeeding 030209 endocrinology & metabolism Pilot Projects Thoracic Vertebrae 03 medical and health sciences 0302 clinical medicine Lumbar Bone Density Lactation medicine Humans Orthopedics and Sports Medicine Femoral neck Gynecology Bone mineral Lumbar Vertebrae Anthropometry Obstetrics business.industry Femur Neck musculoskeletal system medicine.disease Hormones Menstruation 030104 developmental biology medicine.anatomical_structure Breast Feeding Pill Orthopedic surgery Female business Follow-Up Studies |
| Zdroj: | Archives of osteoporosis. 12(1) |
| ISSN: | 1862-3514 |
| Popis: | This pilot study enrolled 31 women who had breastfed exclusively for 6 months. Lumbar and thoracic BMD increased 4 and 5%, respectively. Femoral neck and total body BMD did not change. Return of menses and progestin-only pill use were two potential signals that predicted a greater increase in BMD. The skeleton is resorbed during lactation to provide much of the calcium content of milk. After lactation ceases, these deficits in skeletal mineral content are largely restored, such that lactation has a neutral or protective effect against the long-term risk of low bone mineral density (BMD), osteoporosis, and fragility fractures. We hypothesized that a large observational study may identify the factors that predict a greater increase in BMD after lactation ceases. A pilot study was first needed to test feasibility and the magnitude of expected BMD change. We undertook Factors Affecting Bone formation after Breastfeeding Pilot (FABB Pilot), which enrolled women who had breastfed exclusively for 6 months and planned to wean soon. The main outcome was change in BMD between enrolment and 6 months later. Thirty-one women were recruited and completed both time points. Lumbar and thoracic spine BMD increased 4 and 5%, respectively; there was no significant change in femoral neck and total body BMD. Most women did not wean their babies as planned but continued to breastfeed multiple times per day. Despite this, a significant increase in BMD was seen in the subsequent 6 months. Return of spontaneous menses and use of a progestin-only pill at recruitment were two potential signals that predicted a greater increase in BMD during the 6 months after exclusive lactation. Spine BMD increased significantly during 6 months following exclusive lactation and despite continued lactation. The factors that stimulate skeletal recovery remain to be identified. |
| Databáze: | OpenAIRE |
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