Study of the association between histo-blood group antigens and norovirus infection in Chinese children
| Autor: | Kun-Long Yan, Yu Jin, Wei-Xia Cheng, Zhu-Lun Zhuang |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Diarrhea Male Saliva medicine.medical_specialty China viruses 030106 microbiology Biology medicine.disease_cause Asymptomatic 03 medical and health sciences fluids and secretions Medical microbiology Virology Genotype medicine Humans Genetic Predisposition to Disease Caliciviridae Infections Norovirus Case-control study virus diseases Infant General Medicine Gastroenteritis Case-Control Studies Child Preschool Blood Group Antigens Female medicine.symptom |
| Zdroj: | Archives of virology. 162(11) |
| ISSN: | 1432-8798 |
| Popis: | Human caliciviruses (HuCVs) have been recognized as a major cause of sporadic viral diarrhea in children, among which norovirus genotype GII.4 is the most prevalent genotype. Stool and saliva samples were collected from 295 children with acute diarrhea and 150 asymptomatic children at a hospital in China. The HuCV detection rate was 10.85% (32/295) among the children with acute diarrhea, and all of these 32 children were either HBGA secretors (12/32) or partial secretors (20/32). HuCV was detected in two (1.33%) of the 150 samples obtained from the asymptomatic children. Of the norovirus-GII.3-positive children, 60% had blood type O, but only 17.29% of the symptomatic patients had blood type O, indicating that type O individuals could be at higher risk of GII.3 infection. However, due to the limited number of individuals in this study, further studies with a larger number of subjects should be conducted to verify this hypothesis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink