Changes in Corneal Biomechanical Properties After Descemet Membrane Endothelial Keratoplasty
| Autor: | Fanouria Giasoumi, Sebastian Siebelmann, Bjoern O. Bachmann, Werner Adler, Ludwig M. Heindl, Eleftheria Christofi, Robert Siggel, Claus Cursiefen |
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| Rok vydání: | 2019 |
| Předmět: |
Male
Intraocular pressure medicine.medical_specialty genetic structures Descemet membrane Fuchs Endothelial Dystrophy Cornea Corneal hysteresis 03 medical and health sciences 0302 clinical medicine Ophthalmology Humans Medicine In patient Prospective Studies Aged Aged 80 and over business.industry Fuchs' Endothelial Dystrophy Middle Aged Elasticity eye diseases Biomechanical Phenomena Descemet Stripping Endothelial Keratoplasty 030221 ophthalmology & optometry Female sense organs business 030217 neurology & neurosurgery |
| Zdroj: | Cornea. 38:964-969 |
| ISSN: | 0277-3740 |
| DOI: | 10.1097/ico.0000000000001986 |
| Popis: | Purpose: To evaluate the course of corneal biomechanical properties (corneal hysteresis and corneal resistance factor) after Descemet membrane endothelial keratoplasty (DMEK) in patients with Fuchs endothelial dystrophy (FECD). Methods: In this prospective study, we consecutively included 49 patients with FECD with an indication for DMEK. Central corneal thickness, measured using the Oculus Pentacam, and corneal hysteresis (CH) and corneal resistance factor (CRF), both measured using the Reichert Ocular Response Analyzer, were examined preoperatively, 3 months, and 6 months after DMEK. Results: CH was significantly increased 6 months postoperatively (8.66 +/- 2.50 mm Hg) compared with preoperative baseline (7.43 +/- 1.56 mm Hg). Preoperative CRF (7.89 +/- 1.68 mm Hg) increased significantly 6 months after DMEK (8.49 +/- 1.71 mm Hg). Preoperative central corneal thickness showed a significant decrease from 629 +/- 58 mm to 550 +/- 40 mm after 3 months and 535 +/- 40 mm after 6 months postoperatively. Conclusions: DMEK affects both measured corneal biomechanical properties in patients with FECD: CH and CRF. This has to be taken into account for the accuracy of intraocular pressure measurements. |
| Databáze: | OpenAIRE |
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