Fatigue and immune activity in Sjogren's syndrome

Autor: T.M. Vriesendorp, Cornelis Kallenberg, H.I. Bax, W W I Kalk
Přispěvatelé: Faculteit Medische Wetenschappen/UMCG, Translational Immunology Groningen (TRIGR), Medical Microbiology & Infectious Diseases
Jazyk: angličtina
Rok vydání: 2002
Předmět:
Zdroj: Annals of the Rheumatic Diseases, 61(3), 284-284. BMJ PUBLISHING GROUP
Annals of the Rheumatic Diseases, 61(3). BMJ Publishing Group
ISSN: 0003-4967
Popis: Despite major desiccation of mucous membranes in Sjogren's syndrome (SS), fatigue is often experienced by patients as the most disabling complaint.1,2 Unfortunately, there is no proper treatment available to combat the fatigue in SS. Beside a variety of somatic and non-somatic conditions,2–6 increased immune activity has been implicated as a cause of fatigue in autoimmune diseases.6,7 If responsible for fatigue in SS, it could serve as a treatment target. The purpose of this study was, therefore, to examine the relation between fatigue and immune variables in SS. Thirty six consecutive patients with primary SS visiting our outpatient departments participated in this study. Two control groups were used: a group of 18 patients diagnosed with secondary SS, and a group …
Databáze: OpenAIRE