Fatigue and immune activity in Sjogren's syndrome
Autor: | T.M. Vriesendorp, Cornelis Kallenberg, H.I. Bax, W W I Kalk |
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Přispěvatelé: | Faculteit Medische Wetenschappen/UMCG, Translational Immunology Groningen (TRIGR), Medical Microbiology & Infectious Diseases |
Jazyk: | angličtina |
Rok vydání: | 2002 |
Předmět: |
Male
medicine.medical_specialty Letter business.industry Depression Immunology Disease General Biochemistry Genetics and Molecular Biology DISEASE Treatment targets Immune system Sjogren's Syndrome Rheumatology Internal medicine Case-Control Studies medicine Immunology and Allergy Proper treatment Humans Regression Analysis Female Sjogren s business Fatigue |
Zdroj: | Annals of the Rheumatic Diseases, 61(3), 284-284. BMJ PUBLISHING GROUP Annals of the Rheumatic Diseases, 61(3). BMJ Publishing Group |
ISSN: | 0003-4967 |
Popis: | Despite major desiccation of mucous membranes in Sjogren's syndrome (SS), fatigue is often experienced by patients as the most disabling complaint.1,2 Unfortunately, there is no proper treatment available to combat the fatigue in SS. Beside a variety of somatic and non-somatic conditions,2–6 increased immune activity has been implicated as a cause of fatigue in autoimmune diseases.6,7 If responsible for fatigue in SS, it could serve as a treatment target. The purpose of this study was, therefore, to examine the relation between fatigue and immune variables in SS. Thirty six consecutive patients with primary SS visiting our outpatient departments participated in this study. Two control groups were used: a group of 18 patients diagnosed with secondary SS, and a group … |
Databáze: | OpenAIRE |
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