Pattern of liver function tests in morbidly obese Saudi patients undergoing bariatric surgery
| Autor: | Mohammed Al Shehri, Ahmad El Zubier, Ahmad M Al Akwaa |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Adult
Male medicine.medical_specialty Cirrhosis Saudi Arabia Risk Assessment Body Mass Index Cohort Studies Age Distribution Postoperative Complications Liver Function Tests medicine Humans lcsh:RC799-869 Sex Distribution Retrospective Studies Ultrasonography Bariatric surgery medicine.diagnostic_test business.industry Incidence Fatty liver Gastroenterology medicine.disease morbidly obese Obesity Morbid Surgery Fatty Liver Obstructive sleep apnea Treatment Outcome Liver biopsy Abdominal ultrasonography Abnormal Liver Function Test lcsh:Diseases of the digestive system. Gastroenterology Female Original Article Liver function tests business Body mass index Follow-Up Studies |
| Zdroj: | Saudi Journal of Gastroenterology : Official Journal of the Saudi Gastroenterology Association The Saudi Journal of Gastroenterology, Vol 17, Iss 4, Pp 252-255 (2011) |
| ISSN: | 1319-3767 |
| DOI: | 10.4103/1319-3767.82579 |
| Popis: | Background/Aim: Morbidly obese patients have a high prevalence of fatty liver disease and its serious complications, and high prevalence of abnormal liver function tests (LFT). The LFT can give a clue to the liver damage and correlate with activity. We aim to study the pattern of LFT in morbidly obese Saudi patients undergoing bariatric surgery in Eastern region. Patients and Methods: Medical records of patients undergoing bariatric surgery were reviewed. Demographic data, comorbid conditions, and medications taken were recorded. Intraoperative liver appearance was noted. Patients with alcohol intake or without LFT were excluded. Results: Out of 113 patients, 15 patients were excluded, and of the remaining 98 patients analyzed, 58.2% were females. Mean age was 33.1 ± 8.87 years. Mean body mass index (BMI) was 53.7 ± 1.27 kg/m 2 . Abnormal LFT (alanine aminotransaminase (ALT), aspartate aminotransaminase (AST) alkaline phosphatase (ALK), and Gamma glutamyl transpeptidase (GTT) were observed in 17.3%, with 1.5 to 2 times the upper limit of normal. ALT was most elevated in 12.2%. Abdominal ultrasonography was done in 67 (68.4%) patients, of whom 51 (76%) had fatty liver. Comorbid conditions including diabetes mellitus, hypertension, hyperlipidemia, bronchial asthma, and obstructive sleep apnea were observed in 51 (51.50%) patients, eight of them (16.3%) had abnormal LFT. No intraoperative changes of cirrhosis were observed. Conclusion: The prevalence of abnormal LFT is low in morbidly obese patients from the eastern region of Saudi Arabia. A prospective study with a larger sample and liver biopsy, is needed to clarify the findings. |
| Databáze: | OpenAIRE |
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