Negative best-effort design of three-helix bundles composed of atypical loop motifs

Autor: Sakuma Koya
Rok vydání: 2021
Předmět:
DOI: 10.5281/zenodo.5512548
Popis: The typicality of local structures strongly determines the whole fate of the protein design. Here we provided bad examples for such protein design: the backbone structure composed of atypical loop motifs. Such structures are difficult to design even if sequence designs are performed in the best-effort manners.
Databáze: OpenAIRE