Difficulties Reported by Hiv-Infected Patients Using Antiretroviral Therapy in Brazil
| Autor: | Gustavo Machado Rocha, Felipe Melo Teixeira de Freitas, Ramiro d' Avila Rivelli Teixeira, Lorenza Nogueira Campos, Felipe Augusto Souza Gualberto, Mark Drew Crosland Guimarães, Fábio M. de Castilho |
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| Rok vydání: | 2008 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Referral Anti-HIV Agents Cross-sectional study Clinical Sciences Modifiable Factors HIV Infections Logistic regression Patient Perception Health Services Accessibility Young Adult Quality of life Acquired immunodeficiency syndrome (AIDS) Risk Factors Antiretroviral Therapy Highly Active Internal medicine medicine Humans Prospective Studies Young adult Adverse effect Psychiatry lcsh:R5-920 business.industry General Medicine medicine.disease AIDS Treatment Cross-Sectional Studies Logistic Models Treatment Outcome Socioeconomic Factors Adherence Pill Quality of Life Patient Compliance Female lcsh:Medicine (General) business Brazil |
| Zdroj: | Clinics, Vol 63, Iss 2, Pp 165-172 (2008) Clinics, Volume: 63, Issue: 2, Pages: 165-172, Published: 2008 Clinics; v. 63 n. 2 (2008); 165-172 Clinics; Vol. 63 Núm. 2 (2008); 165-172 Clinics; Vol. 63 No. 2 (2008); 165-172 Clinics Universidade de São Paulo (USP) instacron:USP Clinics (Sao Paulo, Brazil) |
| ISSN: | 1807-5932 1980-5322 |
| Popis: | OBJECTIVE: To describe the degree of difficulty that HIV-infected patients have with therapy treatment. INTRODUCTION: Patients perceptions about their treatment are a determinant factor for improved adherence and a better quality of life. METHODS: Two cross-sectional analyses were conducted in public AIDS referral centers in Brazil among patients initiating treatment. Patients interviewed at baseline, after one month, and after seven months following the beginning of treatment were asked to classify and justify the degree of difficulty with treatment. Logistic regression was used for analysis. RESULTS: Among 406 patients initiating treatment, 350 (86.2%) and 209 (51.5%) returned for their first and third visits, respectively. Treatment perceptions ranged from medium to very difficult for 51.4% and 37.3% on the first and third visits, respectively. The main difficulties reported were adverse reactions to the medication and scheduling. A separate logistic regression indicated that the HIV-seropositive status disclosure, symptoms of anxiety, absence of psychotherapy, higher CD4+ cell count (>; 200/mm³) and high (>; 4) adverse reaction count reported were independently associated with the degree of difficulty in the first visit, while CDC clinical category A, pill burden (>; 7 pills), use of other medications, high (>; 4) adverse reaction count reported and low understanding of medical orientation showed independent association for the third visit. CONCLUSIONS: A significant level of difficulty was observed with treatment. Our analyses suggest the need for early assessment of difficulties with treatment, highlighting the importance of modifiable factors that may contribute to better adherence to the treatment protocol. |
| Databáze: | OpenAIRE |
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