Outcome of Descemet stripping automated endothelial keratoplasty in eyes with an Ahmed glaucoma valve
| Autor: | Vito Romano, Colin E. Willoughby, Mark Batterbury, Vivian W. M. Ho, Stephen B. Kaye, Patrick J Chiam, Robert Cheeseman, Anshoo Choudhary |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Male Intraocular pressure medicine.medical_specialty Visual acuity Time Factors genetic structures Visual Acuity Glaucoma Glaucoma valve Endothelial keratoplasty Corneal Diseases 03 medical and health sciences Cellular and Molecular Neuroscience 0302 clinical medicine Ophthalmology Medicine Humans DSAEK Glaucoma Drainage Implants Survival rate Intraocular Pressure Aged Retrospective Studies Aged 80 and over AGV business.industry Graft Survival Retrospective cohort study Ahmed glaucoma valve Middle Aged medicine.disease Descemet stripping automated endothelial keratoplasty Sensory Systems Glaucoma drainage device Descemet Stripping Endothelial Keratoplasty 030221 ophthalmology & optometry Female medicine.symptom business 030217 neurology & neurosurgery Graft survival Follow-Up Studies |
| Zdroj: | GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY |
| ISSN: | 1435-702X |
| Popis: | The purpose was to investigate the survival of Descemet stripping automated endothelial keratoplasty (DSAEK) in eyes with an Ahmed glaucoma valve (AGV). The study had a retrospective case-series of patients with an AGV in the anterior chamber undergoing a DSAEK. Included in the analysis were graft size, number of previous operations, post-operative glaucoma medications, post-operative intraocular pressure (IOP) control, graft size and donor factors (age, endothelial cell density, and post-mortem time). A generalised linear model with binary logistic regression was used to test for an effect on graft survival at 1 year and 1.5 years. Fourteen eyes from 13 patients were included. The survival rate of the first DSAEK at 6, 12, 18, 24 and 30-months was 85%, 71%, 50%, 36% and 30%, respectively. The mean duration to graft failure was 12.9 ± 6.2 months. Five of the seven failed first grafts went on to have a repeat DSAEK. The mean follow-up in this subgroup was 30.7 ± 18.4 months. The survival rate of second DSAEK at 6, 12, 18 and 24 months was 100% (5/5), 100% (5/5), 75% (3/4) and 67% (2/3). Only one second DSAEK failed in the duration of the study and went on to receive a third DSAEK which failed at 18-months. The mean IOP within the first year was significantly lower for grafts that survived at 1 and 1.5 years (17.4 mmHg, 16.9 mmHg) than for grafts that failed (19.4 mmHg, 19.4 mmHg) (p = 0.04, p = 0.009). DSAEK is a viable alternative to PK to restore visual function in eyes with an AGV sited in the anterior chamber. IOP is an important risk factor for graft failure. |
| Databáze: | OpenAIRE |
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