Egg-shell like Calcification as a Protective Factor for Splenic Artery Aneurysm Dilatation
| Autor: | Katsuyuki Hoshina, Takuya Kawahara, Kota Yamamoto, Toshihiko Isaji, Toshio Takayama, Masaya Sano, Takafumi Akai, Masaru Kimura |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Aneurysm Ruptured 030204 cardiovascular system & hematology Risk Assessment Asymptomatic 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Aneurysm Risk Factors Internal medicine Hypertension Portal Linear regression Humans Medicine Risk factor Vascular Calcification Aged Retrospective Studies Aged 80 and over Univariate analysis business.industry General Medicine Middle Aged Prognosis medicine.disease Comorbidity Asymptomatic Diseases Cardiology Portal hypertension Female Surgery medicine.symptom Cardiology and Cardiovascular Medicine business Splenic Artery Dilatation Pathologic Calcification |
| Zdroj: | Annals of Vascular Surgery. 63:193-197 |
| ISSN: | 0890-5096 |
| DOI: | 10.1016/j.avsg.2019.08.102 |
| Popis: | Background The purpose of this study was to evaluate the factors associated with asymptomatic splenic artery aneurysm (SAA) dilatation. Methods Among patients with SAA admitted to our department from 2001 to 2018, 70 lesions in 59 patients were selected and analyzed retrospectively. There were no cases of rupture or pregnancy in the follow-up period. We defined egg-shell appearance as SAA with >75% calcification of the outer shell. We measured the dilatation rate (mm/year) and evaluated the comorbidity and anatomical factors using univariate and multiple linear regression models. Post-hoc multiple linear regression models were fitted to evaluate the possible interactions. Results The mean age was 61.4 years (range 35–85 years), and the initial aneurysm diameter was 15.1 mm (range 3–47 mm). The mean dilatation rate was 0.26 mm/year (range 0–3.2 mm/year) during the follow-up period (average 4.6 years). Univariate analysis revealed that, portal hypertension (PHT) (P = 0.0003), egg-shell appearance (P = 0.007), and aneurysm diameter > 20 mm (P = 0.05) were significantly associated with the dilatation rate. Multivariate analysis revealed that egg-shell appearance was found to be an independent inverse risk factor of dilatation rate (P = 0.006). The multivariate analysis, including interaction terms, revealed a stronger effect of PHT and diameter >20 mm in cases with no egg-shell appearance (P = 0.08 and P = 0.05 for interactions, respectively). Conclusions The egg-shell appearance of SAA was an independent inverse risk factor affecting the SAA dilatation rate. The dilatation rates in the case of PHT and diameter >20 mm were restricted in the presence of the egg-shell appearance. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|