Metabolic Imbalance and Vitamin D Deficiency in Type 1 Diabetes in the Algerian Population
| Autor: | Malha Azzouz, Esma Mihoubi, Nesrine Zaabat, Nabila Attal, Amina Ferhat, R. Raache, M.C. Abbadi, Chafia Touil-Boukoffa, Assia Galleze, Habiba Amroun, Abdelghani Aissou, Hassiba Guettaf-Sadi, Amel Boutemeur, Aissa Boudiba, Zoulikha Aoudia |
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| Rok vydání: | 2018 |
| Předmět: |
Adult
Blood Glucose Male medicine.medical_specialty Endocrinology Diabetes and Metabolism medicine.medical_treatment Population Parathyroid hormone vitamin D deficiency 03 medical and health sciences chemistry.chemical_compound Young Adult 0302 clinical medicine Risk Factors Internal medicine medicine Vitamin D and neurology Immunology and Allergy Humans Insulin Vitamin D education Glycated Hemoglobin education.field_of_study Type 1 diabetes medicine.diagnostic_test C-Peptide business.industry C-peptide medicine.disease Vitamin D Deficiency Endocrinology Diabetes Mellitus Type 1 chemistry Parathyroid Hormone 030220 oncology & carcinogenesis Algeria Case-Control Studies 030221 ophthalmology & optometry Female business Lipid profile Energy Metabolism Biomarkers |
| Zdroj: | Endocrine, metabolicimmune disorders drug targets. 19(8) |
| ISSN: | 2212-3873 |
| Popis: | Background: We aimed to assess Vitamin D levels in patients with Type 1 Diabetes (T1D) and to investigate the correlation between vitamin D and metabolic imbalance. Material and Methods: For our study, we selected thirty-one patients with T1D without complications and fifty-seven healthy controls. Diabetic patients were diagnosed using the criteria of the World Health Organization/American Diabetes Association. Vitamin D, Parathyroid Hormone (PTH), insulin and C peptide assay were performed using chimilunescence. Glucose level, lipid profile, glycated haemoglobin (HbA1c) and ionogram were also analysed. Results: Vitamin D, HbA1c and Gly levels were found to be significant in T1D patients than in controls (P 0. 05) and the results show a non-significant difference of total cholesterol potassium, sodium, phosphor and calcium concentration averages. Conclusion: Our results indicate that the deficiency of VD is associated with an increased risk of T1DM in Algerian population. |
| Databáze: | OpenAIRE |
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