Estimation of sensitivity and specificity of site-specific diagnostic tests

Autor:	W. J. Loesche, Philippe P. Hujoel, L. H. Moulton
Rok vydání:	1990
Předmět:	Pathology medicine.medical_specialty Models Statistical business.industry Diagnostic test Sensitivity and Specificity Correlation Binomial distribution Standard error Predictive Value of Tests Predictive value of tests Statistics medicine Bacteroides Humans Periodontics Treponema Sensitivity (control systems) business Periodontal Diseases Probability
Zdroj:	Journal of Periodontal Research. 25:193-196
ISSN:	1600-0765 0022-3484
DOI:	10.1111/j.1600-0765.1990.tb00903.x
Popis:	Clinical trials designed to estimate the sensitivity and specificity of periodontal diagnostic tests often use multiple sites per patient as experimental units of analyses. Since site-specific test results within a patient are dependent observations, a correlated binomial model should be employed to estimate the sensitivity and specificity of these diagnostic tests. Ignoring the within-patient correlation can result in an over- or underestimation of the true standard errors.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cfbd3b2dd2caea67d67a16513345a6d https://doi.org/10.1111/j.1600-0765.1990.tb00903.x Zobrazit plný text záznamu Plný text