Smartphones and Test Paper-Assisted Ratiometric Fluorescent Sensors for Semi-Quantitative and Visual Assay of Tetracycline Based on the Target-Induced Synergistic Effect of Antenna Effect and Inner Filter Effect
| Autor: | Lei Han, Nian Bing Li, Yu Zhu Yang, Hong Qun Luo, Yu Zhu Fan, Min Qing, Shi Gang Liu |
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| Rok vydání: | 2020 |
| Předmět: |
Paper
Materials science Surface Properties Molecular Conformation 0211 other engineering and technologies Biosensing Techniques 02 engineering and technology 010501 environmental sciences 01 natural sciences Europium Nitriles Animals General Materials Science Particle Size Fluorescent Dyes 0105 earth and related environmental sciences Red fluorescence Detection limit 021110 strategic defence & security studies business.industry Antenna effect Tetracycline Fluorescence Ratiometric fluorescence Milk Spectrometry Fluorescence Linear range Optoelectronics Filter effect Smartphone business Semi quantitative |
| Zdroj: | ACS Applied Materials & Interfaces. 12:47099-47107 |
| ISSN: | 1944-8252 1944-8244 |
| DOI: | 10.1021/acsami.0c15482 |
| Popis: | Development of selective and sensitive methods for on-site assay of tetracycline (TC) is of great significance for public health and food safety. Herein, a valid ratiometric fluorescence strategy using g-C3N4 nanosheets coupled with Eu3+ is designed for the assay of TC. In this strategy, both Eu3+ and g-C3N4 nanosheets serve as the recognition units of TC. The blue fluorescence of g-C3N4 nanosheets can be quenched by TC via the inner filter effect (IFE); meanwhile, the red fluorescence of Eu3+ can be enhanced by TC through the antenna effect (AE). The synergistic effect of AE and IFE caused by TC makes the developed ratiometric fluorescent sensor display a wide linear range for TC from 0.25 to 80 μM with a detection limit of 6.5 nM and a significant fluorescence color evolution from blue to red. Given its simplicity, free-label, excellent selectivity, high sensitivity, and recognizable color change, point-of-care testing systems, including smartphones and test paper-based assays, are developed for the visual sensing of TC. The integration of smartphones and test paper on a ratiometric fluorescent sensor greatly reduces the detection cost and time, providing a promising method for the qualitative discernment and semi-quantitative assay of TC on-site. Moreover, the potential application of the approach is also verified by detecting TC in milk. |
| Databáze: | OpenAIRE |
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