Role of Diffusion-Weighted Magnetic Resonance Imaging in the Diagnosis of Bladder Pain Syndrome/Interstitial Cystitis
| Autor: | Ballerini Daniela, Porru Daniele, Manzoni Federica, La Fianza Alfredo, Spinillo Arsenio, Simeone Claudio, Sala Maria Gabriella, Gardella Barbara, Regina Cesare, Preda Lorenzo, Oworae Howardson Bright, Klersy Catherine, Jallous Hussein, Fiorello Nicolo |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
medicine.medical_specialty Bladder Pain Syndrome Urology Urinary Bladder 030232 urology & nephrology Cystitis Interstitial Pain urologic and male genital diseases 03 medical and health sciences 0302 clinical medicine Statistical significance Female patient medicine Humans Aged medicine.diagnostic_test business.industry Non invasive Urinary Bladder Diseases Interstitial cystitis Cystoscopy Syndrome Middle Aged medicine.disease Diffusion-Weighted Magnetic Resonance Imaging Diffusion Magnetic Resonance Imaging Bladder Biopsy 030220 oncology & carcinogenesis Female Radiology business Genital Diseases Female hormones hormone substitutes and hormone antagonists |
| Popis: | Some recent studies evaluated the introduction of Diffusion Weighted Magnetic Resonance Imaging (DW-MRI) in the diagnosis of Bladder Pain Syndrome/Interstitial Cystitis (BPS/IC). Objective- To evaluate whether DW-MRI can contribute to non-invasive diagnosis of BPS/IC. The agreement between two raters (two radiologists involved in the study) was also evaluated, the relevance of the "operator-dependent" factor defined; Patients and methods- Twenty-two female patients with a diagnosis of BPS-IC were recruited and performed DW-MRI. The same investigation was also performed in 20 patients with pelvic gynecological diseases and no BPS-IC. Results- A significant difference was found between BPS-IC and no-BPS-IC since 17 out of 22 subjects of the first group were positive, compared to 3 out of 20 no-IC subjects, with a P value of 0.001 to highlight the statistical significance. The sensitivity of the exam was 77%, while the specificity was 85%. There was good agreement between the 2 raters in the evaluation of MRI results. Conclusion DW-MRI helps to obtain a non invasive diagnosis of BPS/IC, by providing useful information on the choice of which patients may be more appropriately submitted to cystoscopy and bladder biopsy. |
| Databáze: | OpenAIRE |
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