Urgent Proton Beam Therapy With Interinstitutional Transfer for Patients With Intracranial Rhabdomyosarcoma: Report of 3 Cases
| Autor: | Hiroko Fukushima, Tomohiko Masumoto, Takashi Saito, Hideyuki Sakurai, Yuni Yamaki, Masayuki Noguchi, Ryoko Suzuki, Takashi Fukushima, Tomohei Nakao, Hidetoshi Takada, Sho Hosaka, Masako Inaba, Manabu Minami, Shingo Sakashita, Masashi Mizumoto |
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| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Age at diagnosis Medical information 03 medical and health sciences 0302 clinical medicine Rhabdomyosarcoma Proton Therapy medicine Humans Child Proton therapy Brain Neoplasms business.industry Parameningeal Hematology medicine.disease Radiation therapy Oncology 030220 oncology & carcinogenesis Pediatrics Perinatology and Child Health Parameningeal rhabdomyosarcoma Female Radiology Sarcoma business 030215 immunology |
| Zdroj: | Journal of Pediatric Hematology/Oncology. 42:e12-e17 |
| ISSN: | 1077-4114 |
| DOI: | 10.1097/mph.0000000000001620 |
| Popis: | A number of cases have been reported in recent years regarding the use of proton beam therapy to mitigate adverse events affecting important cranial organs in cases of rhabdomyosarcoma at parameningeal sites. However, few reports have described the use of proton beam therapy as urgent radiotherapy for parameningeal rhabdomyosarcoma with intracranial extension. We treated 3 patients diagnosed with parameningeal rhabdomyosarcoma extending into the cranium who were assessed at other hospitals as suitable for urgent radiotherapy and transferred to our hospital for proton beam therapy. These patients comprised 2 boys and 1 girl 6 to 12 years of age at diagnosis, and proton beam therapy was started on days 5, 11, and 23 after diagnosis, respectively. Patients with parameningeal rhabdomyosarcoma extending into the cranium can be transferred to institutions equipped to perform proton beam therapy. To minimize the interval to starting therapy, medical information should be shared with institutions capable of providing such therapy as soon as the possibility of intracranial soft-tissue sarcoma is recognized. Proton beam therapy is 1 option for radiotherapy in cases of intracranial rhabdomyosarcoma. |
| Databáze: | OpenAIRE |
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