Second outbreak of Trichinella pseudospiralis in Europe: clinical patterns, epidemiological investigation and identification of the etiological agent based on the western blot patterns of the patients' serum

Autor: Giovanni Orefice, Maria Cristina Bisso, Laura Arenare, Maria Angeles Gómez-Morales, Patrizio Pezzotti, Federica Magnè, Giovanni Mazzarello, Marco Amati, Edoardo Pozio, Alessandra Ludovisi, Claudio Viscoli, Elisabetta Bondi, Elio Castagnola
Rok vydání: 2019
Předmět:
0301 basic medicine
Male
Veterinary medicine
Anti-Inflammatory Agents
Trichinella
Trichinella pseudospiralis
Disease Outbreaks
0302 clinical medicine
Trichinella britovi
Food Parasitology
Zoonoses
Epidemiology
Cooking
Child
Anthelmintics
medicine.diagnostic_test
biology
Middle Aged
Infectious Diseases
Italy
Child
Preschool
Female
Original Article
epidemiology
wild boar
Adult
trichinellosis
medicine.medical_specialty
Adolescent
Prednisolone
030106 microbiology
030231 tropical medicine
Trichinella spiralis
Blotting
Western
Albendazole
03 medical and health sciences
Western blot
Wild boar
biology.animal
parasitic diseases
medicine
Animals
Humans
western blot
General Veterinary
General Immunology and Microbiology
outbreak
Public Health
Environmental and Occupational Health
Outbreak
Infant
Original Articles
biology.organism_classification
Red Meat
Etiology
Zdroj: Zoonoses and Public Health
ISSN: 1863-2378
Popis: Trichinellosis is a zoonotic disease due to the ingestion of raw or undercooked meat from animals infected with the larvae of nematodes belonging to the genus Trichinella. In January–February 2015, an outbreak of trichinellosis occurred in Genoa, Northern Italy. The epidemiological link was traced back to a dinner served at an agritourism farm on 31 December 2014, where a majority of the 52 guests had consumed the ‘beef’ steak tartare. The source of infection was not traced; however, it was noted that the amount of beef purchased officially for providing at the dinner did not correspond with that served, suggesting that meat of a different origin had been added to the beef to prepare the steak tartare. Clinical and laboratory data of 30 individuals out of the 52 (57.7%), of which four were hospitalized, were consistent with that of the case definition of trichinellosis. Western blot patterns of the sera from patients with confirmed trichinellosis were similar to the diagnostic pattern identified for the reference sera of Trichinella pseudospiralis but different from those of the control sera tested for patients infected with Trichinella spiralis and Trichinella britovi. Identification of T. pseudospiralis as the aetiological agent responsible for the outbreak of trichinellosis using an indirect tool represents an advancement in the epidemiological investigation of this zoonotic disease.
Databáze: OpenAIRE
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