Two new 2-phenylethylchromones from artificial agarwood by holing method
| Autor: | Pan Xiang, Hui-Qin Chen, Hao-Fu Dai, Wen-Li Mei, Hao Wang, Fan-Dong Kong, Yan-Bo Zeng |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Ethyl acetate
Pharmaceutical Science Aquilaria sinensis engineering.material 01 natural sciences Analytical Chemistry chemistry.chemical_compound Drug Discovery Flavonoids Pharmacology Molecular Structure biology Traditional medicine Phenylpropanoid 010405 organic chemistry Organic Chemistry General Medicine Agarwood biology.organism_classification Wood 0104 chemical sciences 010404 medicinal & biomolecular chemistry Complementary and alternative medicine chemistry Thymelaeaceae Chromone Acetylcholinesterase engineering Molecular Medicine Cholinesterase Inhibitors |
| Zdroj: | Journal of Asian Natural Products Research. 23:1156-1163 |
| ISSN: | 1477-2213 1028-6020 |
| DOI: | 10.1080/10286020.2020.1860029 |
| Popis: | Two new 2-(2-phenylethyl)chromone derivatives (1–2) were isolated from the ethyl acetate extract of artificial agarwood induced by holing method originating from Aquilaria sinensis (Lour.) Gilg, and they were isolated from this genus for the first time. The structures of these two new compounds were elucidated by extensive spectroscopic analyses, including UV, IR, one- and two-dimensional NMR and HRESIMS measurements. Bioassay tests of these two new compounds showed compounds 1 and 2 had weak inhibitory activity against acetylcholinesterase at a concentration of 50.0 μg/ml. |
| Databáze: | OpenAIRE |
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