Supplementary Figure 3 from Effective Clinical Responses in Metastatic Melanoma Patients after Vaccination with Primary Myeloid Dendritic Cells

Autor: I. Jolanda M. de Vries, Carl G. Figdor, Cornelis J.A. Punt, Winald R. Gerritsen, Christian U. Blank, Sander Kelderman, Joannes F.M. Jacobs, Rutger H.T. Koornstra, Sandra A.J. Croockewit, Roel D.M. Mus, Marieke E.B. Welzen, Michelle M. van Rossum, Willeke A.M. Blokx, Katja Petry, Gregor Winkels, Jurjen Tel, Tom G.M. van Oorschot, Michel A.M. Olde Nordkamp, Jeanette M. Pots, Annemiek J. de Boer, Nicole M. Scharenborg, Mandy W.M.M. van de Rakt, Tjitske Duiveman-de Boer, Erik H.J.G. Aarntzen, Florian Wimmers, Harm Westdorp, Kalijn F. Bol, Gerty Schreibelt
Rok vydání: 2023
DOI: 10.1158/1078-0432.22457933.v1
Popis: Supplementary Figure 3. KLH-specific immune responses before and after DC vaccination. (A) KLH-specific T cell proliferation was analyzed before the first vaccination and after each DC vaccination during the first vaccination cycle in peripheral blood of vaccinated metastatic melanoma patients. Per time point each dot represents 1 patient. Proliferative response to KLH is given as proliferation index (proliferation with KLH/proliferation without KLH). The two patients not showing a KLH-specific T cell response are shown in grey. (B) KLH-specific IgG, IgA, and IgM antibodies were quantitatively measured after each vaccination cycle in sera of vaccinated patients. Per isotype each dot represents one patient. Best KLH responses per patient are shown.
Databáze: OpenAIRE