Surgical complications and outcome of pediatric liver transplantation in Hong Kong
| Autor: | Htut Saing, Kwok-Yung Yuen, Paul K.H. Tam, Kwong-Leung Chan, John Wong, Irene Oi-Lin Ng, Sheung Tat Fan, N.S. Tsoi, William I. Wei, Wai Kuen Tso, M.T. Chau, Chung Mau Lo |
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| Rok vydání: | 2002 |
| Předmět: |
Male
medicine.medical_specialty medicine.medical_treatment Liver transplantation Pseudoaneurysm Postoperative Complications Humans Medicine Child Intraoperative Complications Vein Survival rate Hepatitis business.industry Incidence Infant General Medicine medicine.disease Tissue Donors Liver Transplantation Surgery Portal vein thrombosis Survival Rate Transplantation Treatment Outcome medicine.anatomical_structure Child Preschool Pediatrics Perinatology and Child Health Hong Kong Female Complication business |
| Zdroj: | Journal of Pediatric Surgery. 37:1673-1677 |
| ISSN: | 0022-3468 |
| Popis: | Purpose: The aim of this study was to analyze the early and late results of pediatric liver transplantation, with particular reference to complications that required surgical or radiologic intervention. Methods: The records and code sheets of children who underwent liver transplantation in the authors' institution between September 1993 and December 2001 were reviewed. Results: Twenty-nine children (16 boys and 13 girls) underwent 31 liver transplantations (23 living donor, 8 cadaveric donor) during the study period. The ages of the children ranged from 4 months to 132 months (median, 16 months). Eighteen children had complications that required surgical or radiologic interventional procedures. Complications included, among others, hepatic vein thrombosis (n = 1, 3%), hepatic vein stenosis (n = 2, 7%), portal vein thrombosis (n = 2, 7%), biliary stricture (n = 3, 10%), bile leakage (n = 2, 7%), hepatic artery pseudoaneurysm (n = 1, 3%), jejuno-jejunostomy leakage (n = 1, 3%), graft hepatitis (n = 1, 3%), and posttransplant lymphoproliferative disorder (n = 2, 7%). In addition, 6 children (21%) suffered from intraabdominal bleeding from a variety of causes. After appropriate interventions, at a median follow-up of 38 months (range, 1 to 96 months), patient and graft survival rates were 79% and 74%, respectively. The retransplantation rate was only 7%. There was no incidence of hepatic artery thrombosis. All living donors remain alive and well. Conclusions: Complications are inevitable in pediatric liver transplantation. However, with timely recognition and active intervention, a good outcome can be achieved. J Pediatr Surg 37:1673-1677. Copyright 2002, Elsevier Science (USA). All rights reserved. |
| Databáze: | OpenAIRE |
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