Prevalence of inherited prothrombotic abnormalities and central venous catheter-related thrombosis in haematopoietic stem cell transplants recipients
| Autor: | N Ben Romdhane, Lamia Torjman, A. Ben Abdeladhim, Fethi Ladeb, T. Ben Othman, A Ben Hassen, Mouna Chelli, Saloua Ladeb, S. Guermazi, Amel Lakhal, Abderrahman Abdelkefi, A Kriaa |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Male
Catheterization Central Venous medicine.medical_specialty medicine.medical_treatment Gastroenterology Catheterization Internal medicine Prevalence medicine Factor V Leiden Humans Thrombophilia Genetic Predisposition to Disease Prospective Studies Protein S deficiency Family Health Transplantation Catheter insertion business.industry Antithrombin Hematopoietic Stem Cell Transplantation Thrombosis Hematology Middle Aged medicine.disease Blood Coagulation Factors Surgery Venous thrombosis Female business Central venous catheter Protein C medicine.drug |
| Zdroj: | Bone Marrow Transplantation. 36:885-889 |
| ISSN: | 1476-5365 0268-3369 |
| DOI: | 10.1038/sj.bmt.1705156 |
| Popis: | In this prospective study, we assessed the incidence of central venous catheter (CVC)-related thrombosis in haematopoietic stem cell transplant (HSCT) recipients. We determined the contribution of inherited prothrombotic abnormalities in blood coagulation to CVC-related thrombosis in these patients. The study was conducted between May 2002 and September 2004. CVCs were externalized, nontunneled, polyurethane double lumen catheters. Before catheter insertion, laboratory prothrombotic markers included factor V Leiden, the prothrombin gene Gly20210A mutation, plasma antithrombin levels, and protein C and S activity. All patients were systematically examined by ultrasonography just before, or |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|