Induced hypotension for functional endoscopic sinus surgery: A comparative study of dexmedetomidine versus esmolol
| Autor: | Ragaa El-Masry, Mohamed Abu-Samra, Nahla S El Bahnasawe, Tarek Shams |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
business.industry Sedation dexmedetomidine esmolol Esmolol Loading dose functional endoscopic sinus surgery Sevoflurane Fentanyl Surgery lcsh:RD78.3-87.3 Anesthesiology and Pain Medicine lcsh:Anesthesiology Anesthesia Anesthetic medicine Arterial blood Original Article Dexmedetomidine medicine.symptom Controlled hypotension business medicine.drug |
| Zdroj: | Saudi Journal of Anaesthesia Saudi Journal of Anaesthesia, Vol 7, Iss 2, Pp 175-180 (2013) |
| ISSN: | 1658-354X |
| DOI: | 10.4103/1658-354x.114073 |
| Popis: | Objective: A comparative study to evaluate the efficacy of dexmedetomidine as a hypotensive agent in comparison to esmolol in Functional Endoscopic Sinus Surgery (FESS). Methods: Forty patients ASA I or II scheduled for FESS were equally randomly assigned to receive either dexmedetomidine 1 μg/Kg over 10 min before induction of anesthesia followed by 0.4-0.8 μg/Kg/h infusion during maintenance (DEX group), or esmolol, loading dose 1mg/kg was infused over one min followed by 0.4-0.8 mg/kg/h infusion during maintenance (E group) to maintain mean arterial blood pressure (MAP) between (55-65 mmHg). General anesthesia was maintained with sevoflurane 2%-4%. The surgical field was assessed using Average Category Scale and average blood loss was calculated. Hemodynamic variables (MAP and HR); arterial blood gas analysis; plasma cortisol level; intraoperative fentanyl consumption; Emergence time and total recovery from anesthesia (Aldrete score ≥9) were recorded. Sedation score was determined at 15, 30, 60 min after tracheal extubation and time to first analgesic request was recorded. Result: Both DEX group and E group reached the desired MAP (55-65 mmHg) with no intergroup differences in MAP or HR. The for the quality of the surgical filed in the range of MAP (55-65 mmHg) were |
| Databáze: | OpenAIRE |
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