Daily-Diary Evaluated Side-Effects of Conformal versus Conventional Prostatic Cancer Radiotherapy Technique
| Autor: | Roger Henriksson, Lars Franzén, Bo Littbrand, Per Fransson, Anders Widmark |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Diarrhea
Male medicine.medical_specialty Sucralfate Urinary system medicine.medical_treatment Urology Pain Medical Records Placebos Feces Prostate cancer Double-Blind Method Gastrointestinal Agents Prostate medicine Humans Radiology Nuclear Medicine and imaging Prospective Studies Defecation Urinary Tract Prospective cohort study Hematuria Neoplasm Staging Radiotherapy business.industry Prostatic Neoplasms Cancer Radiotherapy Dosage Hematology General Medicine Urination Disorders medicine.disease Abdominal Pain Surgery Intestines Radiation therapy medicine.anatomical_structure Oncology Evaluation Studies as Topic Case-Control Studies Complication business Follow-Up Studies medicine.drug |
| Zdroj: | Acta Oncologica. 36:499-507 |
| ISSN: | 1651-226X 0284-186X |
| Popis: | Conventional 4-field box radiotherapy technique induces high morbidity for patients with localized prostatic cancer. Using a patient daily diary, the present study compared side-effects after conventional radiotherapy with conformal radiotherapy for prostate cancer. Fifty-eight patients treated with the conventional technique (with or without sucralfate) were compared with 72 patients treated with conformal technique. The patient groups were compared with an age-matched control population. Patients treated with conformal technique were also evaluated regarding acute and late urinary problems. Results showed that patients treated with conformal technique reported significantly fewer side-effects as compared with conventional technique. Patients treated with sucralfate also showed slightly decreased intestinal morbidity in comparison to non-sucralfate group. Acute and late morbidity evaluated by the patients was decreased after conformal radiotherapy as compared with the conventional technique. Sucralfate may be of value if conformal radiotherapy is used for dose escalation in prostatic cancer patients. |
| Databáze: | OpenAIRE |
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